Is there somewhere in ISPC that I can tell it what port to look for? I use the following settings in my /etc/postfix/master.cf #smtp inet n - - - - smtpd 125 inet n - - - - smtpd I am seeing this with the latest build of ISPC on Ubuntu 14.x and a new Debian Jessie build. Thanks!
add a line: 127.0.0.1:smtp inet n - - - - smtpd and restart postfix so ISPConfig can find the smtp daemn again.