Real quick one; is it going to cause any long term problems if I change the port that the ISPConfig web server (for the web interface of ISPConfig itsself) listens on in the NGINX config file from 8080 to 443, is that going to cause me problems down the road? Or should it not really have any problem. I saw an old thread saying you have to set it to the port you want at install but it was back in 2017.
i believe you'd have to edit the vhost config for it so that it only uses the server name, otherwise it'll cause problems for all the other sites on the server. (unless you're going multi-server and only having the ispconfig interface installed on that particular server) maybe a better option for you would be to create a website using a different subdomain,, eg mypanel, panel, cp or similar, and configure that to reverse proxy to https://<hostname.yourdomain.tld>:8080 instead..
Currently the only thing I'm using it for is email. I have two vhost files currently, the one for the default ISPConfig site and then another that leads to the roundcube email client. Putting both in different server blocks and having them listen on 443 seems to work fine I just wasn't sure if it was going to mess with anything else at all.