Good morning, Is it possible to change apache to nginx in an installed ispconfig? What is the procedure?
I believe it is not easy. If it must be done, I would install a new ISPConfig system with nginx. and use migration tool to move the data to that.
Like @Taleman mentioned, its possible but not easy. Also, probably most of your existing sites will stop working, at least if they rely on Apache features like .htaccess, you would have to convert any .htaccess file to Nginx config syntax and add that config in Nginx directives field of the website.
IMHO adding nginx BETWEEN apache and user is the best method. NGINX can handle what it can (static resources) and pass the rest to apache.