Hello world! For the last 12 hours I was digging deep into Google results to get a tricky bug out of my freshly installed ISPC on Centos 6: amavis always reported a fatal error when trying to scan an incoming mail. amavis[4260]: (04260-02) (!)ClamAV-clamd av-scanner FAILED: run_av error: Too many retries to talk to /var/spool/amavisd/clamd.sock (Can't connect to UNIX socket /var/spool/amavisd/clamd.sock: No such file or directory) at (eval 90) line 373.\n It seems to be a problem for a lot of people. Several Google results advised to change the path so clamd.sock in the amavisd.conf and clamd.conf. But nothing helped. But as the spool folder is only a temporary folder, its content must be created somehow at the startup of some service. That pointed me to the right direction: chkconfig clamd.amavisd on It starts clamd for amavisd at boot time and therefore creates the clamd.sock, so it can be accessed. Maybe it saves someone else's day...