I've been running ISPConfig3 on a VPS since 2011, and I've always played with this type of setup. I'm starting to have issues with email and spam though, causing issues with my configuration. Just wanted to hear anyone else's experience with ISPConfig 3 running on a VPS, running Web, SQL, Mail, DNS, and any other stuff... Oh, and my VPS is at MyHosting.com, which I've had good success for the past years =)
It does not matter for an ISPConfig setup if it is run on a VPS or a dedicated server. I run most of my servers on VPS.