I've noticed that when you activate/deactive a mail domain, ispconfig will reload amavis, but not postfix. This is a problem because to let postfix see the modify you had to realod postfix too.
You don't have to reload postfix when you add or delete a domain on an ISPConfig server. Postfix reads this data directly out of the MySQL database in realtime, so a reload is not required. Amavis is reloaded as Dkim changes the amavisd configuration file.
I've found that to work i've manually to reload postfix. I'm doubt that heappen because the tomain i've test is configured as mail routing and Reley recipient?
It's not nescessary. I riún several relay servers here as well and I never had to reload Postfix on an ISPConfig server for that. I verified it just again here now and the domain is active automatically, no reload required