I had big trouble with my Postfix mail server and looked in the log and were not seeing any real problem then I remembered that clamd acted strange when I tried to install. My fix (makes me recive email ): Please correct me if I are killing the system.. yum reinstall amavisd-new spamassassin clamav clamd --disablerepo=epel sa-update chkconfig --levels 235 amavisd on # not chkconfig --del clamd # not chkconfig --levels 235 clamd.amavisd on chkconfig --levels 235 clamd on /usr/bin/freshclam /etc/init.d/amavisd start # not /etc/init.d/clamd.amavisd start /etc/init.d/clamd start Guide postfix on Centos 6.4 64: “yum install amavisd-new spamassassin clamav clamd unzip bzip2 unrar perl-DBD-mysql” or “yum install amavisd-new” Gives output Loaded plugins: fastestmirror, presto, priorities Loading mirror speeds from cached hostfile * base: archive.cs.uu.nl * epel: epel.mirror.nucleus.be * extras: archive.cs.uu.nl * rpmforge: archive.cs.uu.nl * updates: nl.mirror.eurid.eu Setting up Install Process Resolving Dependencies --> Running transaction check ---> Package amavisd-new.x86_64 0:2.8.0-1.el6.rf will be updated ---> Package amavisd-new.noarch 0:2.8.0-4.el6 will be an update --> Processing Dependency: unzoo for package: amavisd-new-2.8.0-4.el6.noarch --> Processing Dependency: perl(Razor2::Client::Version) for package: amavisd-ne w-2.8.0-4.el6.noarch --> Processing Dependency: perl(Net::LDAP) for package: amavisd-new-2.8.0-4.el6. noarch --> Processing Dependency: perl(Mail::SPF) for package: amavisd-new-2.8.0-4.el6. noarch --> Processing Dependency: perl(DBD::SQLite) for package: amavisd-new-2.8.0-4.el 6.noarch --> Processing Dependency: perl(Authen::SASL) for package: amavisd-new-2.8.0-4.e l6.noarch --> Processing Dependency: p7zip-plugins for package: amavisd-new-2.8.0-4.el6.no arch --> Processing Dependency: lrzip for package: amavisd-new-2.8.0-4.el6.noarch --> Processing Dependency: /etc/clamd.d for package: amavisd-new-2.8.0-4.el6.noa rch --> Running transaction check ---> Package amavisd-new.noarch 0:2.8.0-4.el6 will be an update --> Processing Dependency: /etc/clamd.d for package: amavisd-new-2.8.0-4.el6.noa rch ---> Package lrzip.x86_64 0:0.614-1.el6 will be installed ---> Package p7zip-plugins.x86_64 0:9.20.1-2.el6 will be installed ---> Package perl-Authen-SASL.noarch 0:2.13-2.el6 will be installed --> Processing Dependency: perl(GSSAPI) for package: perl-Authen-SASL-2.13-2.el6 .noarch ---> Package perl-DBD-SQLite.x86_64 0:1.27-3.el6 will be installed ---> Package perl-LDAP.noarch 1:0.40-1.el6 will be installed --> Processing Dependency: perl(XML::SAX::Writer) for package: 1erl-LDAP-0.40- 1.el6.noarch --> Processing Dependency: perl(XML::SAX::Base) for package: 1erl-LDAP-0.40-1. el6.noarch --> Processing Dependency: perl(Convert::ASN1) for package: 1erl-LDAP-0.40-1.e l6.noarch ---> Package perl-Mail-SPF.noarch 0:2.007-1.el6 will be installed ---> Package perl-Razor-Agent.x86_64 0:2.85-6.el6 will be installed ---> Package unzoo.x86_64 0:4.4-7.el6 will be installed --> Running transaction check ---> Package amavisd-new.noarch 0:2.8.0-4.el6 will be an update --> Processing Dependency: /etc/clamd.d for package: amavisd-new-2.8.0-4.el6.noa rch ---> Package perl-Convert-ASN1.noarch 0:0.22-1.el6 will be installed ---> Package perl-GSSAPI.x86_64 0:0.26-6.el6 will be installed ---> Package perl-XML-SAX-Base.noarch 0:1.04-1.el6.rf will be installed ---> Package perl-XML-SAX-Writer.noarch 0:0.50-8.el6 will be installed --> Processing Dependency: perl(XML::NamespaceSupport) for package: perl-XML-SAX -Writer-0.50-8.el6.noarch --> Processing Dependency: perl(XML::Filter::BufferText) for package: perl-XML-S AX-Writer-0.50-8.el6.noarch --> Processing Dependency: perl(Text::Iconv) for package: perl-XML-SAX-Writer-0. 50-8.el6.noarch --> Running transaction check ---> Package amavisd-new.noarch 0:2.8.0-4.el6 will be an update --> Processing Dependency: /etc/clamd.d for package: amavisd-new-2.8.0-4.el6.noa rch ---> Package perl-Text-Iconv.x86_64 0:1.7-6.el6 will be installed ---> Package perl-XML-Filter-BufferText.noarch 0:1.01-8.el6 will be installed ---> Package perl-XML-NamespaceSupport.noarch 0:1.10-3.el6 will be installed --> Processing Dependency: /etc/clamd.d for package: amavisd-new-2.8.0-4.el6.noa rch --> Finished Dependency Resolution Error: Package: amavisd-new-2.8.0-4.el6.noarch (epel) Requires: /etc/clamd.d Available: clamd-0.97.7-1.el6.x86_64 (epel) Not found Installed: clamd-0.97.7-1.el6.rf.x86_64 (@rpmforge) Not found Available: clamd-0.96.4-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.96.5-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.1-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.2-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.3-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.4-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.5-1.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.5-2.el6.rf.x86_64 (rpmforge) Not found Available: clamd-0.97.6-1.el6.rf.x86_64 (rpmforge) Not found You could try using --skip-broken to work around the problem You could try running: rpm -Va --nofiles --nodigest