Hello! I testing debian9 ispconfig-dev. The openssl 1.1 not support SSLv2. Consequently problem dovecot ispconfig default config, the ssl_protocols part: ssl_protocols = !SSLv2 !SSLv3 The logfile detail: root@debi9mail:/# cat /var/log/mail.err Jun 20 09:46:40 debi9mail dovecot: imap-login: Fatal: Invalid ssl_protocols setting: Unknown protocol 'SSLv2' Jun 20 09:46:40 debi9mail dovecot: pop3-login: Fatal: Invalid ssl_protocols setting: Unknown protocol 'SSLv2' Jun 20 09:46:40 debi9mail dovecot: master: Error: service(imap-login): command startup failed, throttling for 2 secs Jun 20 09:46:40 debi9mail dovecot: master: Error: service(pop3-login): command startup failed, throttling for 2 secs I temporary solution remove !SSLv2 from line: ssl_protocols = !SSLv3