Error while running apache2ctl configtest. Action 'configtest' failed.

I have had ispconfig3 running on apache2 with php7 installed for about a month and I love it.
I enabled ssl and let's encrypt for multiple sites as I added them and then just left it alone to "bake".
I noticed that only one site has ssl enabled so I tried:
letsencrypt --apache
So it would pick up all the virtual domains.
I got the error:
Error while running apache2ctl configtest.
Action 'configtest' failed.
The Apache error log may have more information.

AH00548: NameVirtualHost has no effect and will be removed in the next release /etc/apache2/sites-enabled/000-ispconfig.conf:69
AH00526: Syntax error on line 2 of /etc/apache2/le_tls_sni_01_cert_challenge.conf:
The address or port is invalid
Ports are open in ufw any idea why let's encrypt may not be working?
Forum software will not let me past my log errors in here........