expecting problems running multi server setup on different debian releases?

Hi,
planning upgrading our debian servers from 10 to 11 - ISPConfig 3 in a multi server setup is installed on all - do I have to expect any problems while the major releases (debian 10 / 11) differs for some time (days)? And if not, not even if via seb.sury.org different PHP versions are installed?

Best regards,
cmks