ISPconfig is very cool and I have most of it working. So, my isp blocks port 25 and I have got around this in the past by using rollernet.us and port 2525 with another mail server. I've added to /etc/postfix/master.cf smtp inet n - n - - smtpd 2525 inet n - n - - smtpd I can telnet to both 25 and 2525 ang get regular responses and postfix is running. netstat -tap provides this: Active Internet connections (servers and established) Proto Recv-Q Send-Q Local Address Foreign Address Stat e PID/Program name tcp 0 0 *:imaps *:* LIST EN 1814/xinetd tcp 0 0 *op3s *:* LIST EN 1814/xinetd tcp 0 0 *:49507 *:* LIST EN 1529/rpc.statd tcp 0 0 *:mysql *:* LIST EN 1908/mysqld tcp 0 0 *op3 *:* LIST EN 1814/xinetd tcp 0 0 *:imap *:* LIST EN 1814/xinetd tcp 0 0 *:sunrpc *:* LIST EN 1511/portmap tcp 0 0 *:81 *:* LIST EN 2156/ispconfig_http tcp 0 0 192.168.1.2:domain *:* LIST EN 2418/named tcp 0 0 hidden.dom:domain *:* LIST EN 2418/named tcp 0 0 hidden.dom:ipp *:* LIST EN 1765/cupsd tcp 0 0 hidden.dom:5335 *:* LIST EN 1747/mDNSResponder tcp 0 0 *:smtp *:* LIST EN 3506/master tcp 0 0 hidden.dom:rndc *:* LIST EN 2418/named tcp 0 0 *:2525 *:* LIST EN 3506/master tcp 0 0 *:http *:* LIST EN 2323/httpd tcp 0 0 *:ssh *:* LIST EN 1805/sshd tcp 0 0 localhost:rndc *:* LIST EN 2418/named tcp 0 0 *:https *:* LIST EN 2323/httpd tcp 0 148 ::ffff:192.168.1.2:ssh ::ffff:192.168.1.3:2522 ESTA BLISHED 5264/2 tcp 0 0 ::ffff:192.168.1.2:ssh ::ffff:192.168.1.7:54503 ESTA BLISHED 2792/sshd: snook[pr There is an A record pointing to mail under the domain to the correct global IP. The MX record points to mail.rollernet.us However, when I try to point an email client to mail.domain.com or the IP address I get a mail relay access denied when trying to send.. I'm not sure if the issue is with the local ispconfig server or with rollernet. Or maybe both. When I send an email from an external account it disappears. No bounce and no received email. I've trawled through the forums looking for the answer to this but haven't found it. Probably I've missed something obvious.