Hi Guys, I have a VPS. It had one IP address and it worked well with the ISPConfig's Postfix setup. Then I thought I will buy another IP and will set websites to work with the new IP and the authenticated e-mail users with the old one. So, I configured Postfix in multi instance mode. Created a new instance and moved its settings to the default Postfix configuration, in /etc/postfix/. After this I moved the original one into the new instance's configuration, in /etc/postfix-out/. I had some problems with sasl authentication, but I have managed to solve most of them. Now everything works fine. Websites can send e-mails, and even webmail users can authenticate, receive and send mails, but remote users cannot authenticate with Postfix. It gives SASL LOGIN authentication failed: authentication failure message. It uses MySQL to get users login information, maybe this is the part, where it gets wrong. Here are the main.cf content of the postfix-out instance (I changed the IP address with X.X.X.X, and my domain name of course): smtpd_banner =$myhostname ESMTP $mail_name (Ubuntu) biff = no append_dot_mydomain = no readme_directory =/usr/share/doc/postfix data_directory =/var/lib/postfix-out smtpd_tls_cert_file =/etc/postfix-out/smtpd.cert smtpd_tls_key_file =/etc/postfix-out/smtpd.key smtpd_use_tls = yes smtpd_tls_session_cache_database = btree:${data_directory}/smtpd_scache smtp_tls_session_cache_database = btree:${data_directory}/smtp_scache smtpd_relay_restrictions = permit_mynetworks permit_sasl_authenticated defer_unauth_destination myhostname = mydomain.com alias_maps = hash:/etc/aliases, hash:/var/lib/mailman/data/aliases alias_database = hash:/etc/aliases, hash:/var/lib/mailman/data/aliases mydestination = mydomain.com, localhost, localhost.localdomain relayhost = mynetworks =127.0.0.0/8, X.X.X.X mailbox_command = procmail -a "$EXTENSION" mailbox_size_limit =0 recipient_delimiter =+ inet_interfaces = X.X.X.X,127.0.0.1 inet_protocols = ipv4 html_directory =/usr/share/doc/postfix/html virtual_alias_domains = virtual_alias_maps = hash:/var/lib/mailman/data/virtual-mailman, proxy:mysql:/etc/postfix-out/mysql-virtual_forwardings.cf, proxy:mysql:/etc/postfix-out/mysql-virtual_email2email.cf virtual_mailbox_domains = proxy:mysql:/etc/postfix-out/mysql-virtual_domains.cf virtual_mailbox_maps = proxy:mysql:/etc/postfix-out/mysql-virtual_mailboxes.cf virtual_mailbox_base =/var/vmail virtual_uid_maps = static:5000 virtual_gid_maps = static:5000 smtpd_sasl_auth_enable = yes broken_sasl_auth_clients = yes smtpd_sasl_authenticated_header = yes smtpd_recipient_restrictions = permit_mynetworks, permit_sasl_authenticated, reject_unauth_destination, check_recipient_access mysql:/etc/postfix-out/mysql-virtual_recipient.cf smtpd_tls_security_level = may transport_maps = hash:/var/lib/mailman/data/transport-mailman, proxy:mysql:/etc/postfix-out/mysql-virtual_transports.cf relay_domains = mysql:/etc/postfix-out/mysql-virtual_relaydomains.cf relay_recipient_maps = mysql:/etc/postfix-out/mysql-virtual_relayrecipientmaps.cf proxy_read_maps =$local_recipient_maps $mydestination $virtual_alias_maps $virtual_alias_domains $virtual_mailbox_maps $virtual_mailbox_domains $relay_recipient_maps $relay_domains $canonical_maps $sender_canonical_maps $recipient_canonical_maps $relocated_maps $transport_maps $mynetworks smtpd_sender_restrictions = check_sender_access mysql:/etc/postfix-out/mysql-virtual_sender.cf smtpd_client_restrictions = check_client_access mysql:/etc/postfix-out/mysql-virtual_client.cf smtpd_client_message_rate_limit =100 maildrop_destination_concurrency_limit =1 maildrop_destination_recipient_limit =1 virtual_transport = dovecot header_checks = regexp:/etc/postfix-out/header_checks mime_header_checks = regexp:/etc/postfix-out/mime_header_checks nested_header_checks = regexp:/etc/postfix-out/nested_header_checks body_checks = regexp:/etc/postfix-out/body_checks owner_request_special = no smtp_tls_security_level = may smtpd_tls_mandatory_protocols =!SSLv2,!SSLv3 smtpd_tls_protocols =!SSLv2,!SSLv3 smtp_tls_protocols =!SSLv2,!SSLv3 dovecot_destination_recipient_limit =1 smtpd_sasl_type = cyrus smtpd_sasl_path = smtp.conf cyrus_sasl_config_path =/etc/postfix-out/sasl content_filter = amavis:[127.0.0.1]:10024 receive_override_options = no_address_mappings message_size_limit =0 inet_protocols = ipv4 queue_directory =/var/spool/postfix-out multi_instance_name = postfix-out multi_instance_enable = yes multi_instance_wrapper =${command_directory}/postmulti -p -- What am I missing? Thanks for your help in advance!