Roundcube getting error on new server in multiserver setup

Have a multiserver setup and installed a new webserver that includes having roundcube installed on it using:
https://www.howtoforge.com/using-roundcube-webmail-with-ispconfig-3-on-debian-wheezy-apache2
I can access webmail using the server name, but not when using a domain that is on that server

http://servername.com/webmail <- I get the roundcube login screen

http://my_domain.com/webmail <- get a 500 error

Looking at the error log for the website I see these errors:
[Wed Aug 12 13:06:28 2015] [error] [client 76.xx.xx.24] PHP Warning: require_once(): open_basedir restriction in effect. File(/usr/share/roundcube/program/include/iniset.php) is not within the allowed path(s): (/var/www/clients/client66/web187/web:/var/www/clients/client66/web187/private:/var/www/clients/client66/web187/tmp:/var/www/domainguyz.com/web:/srv/www/domainguyz.com/web:/usr/share/php5:/usr/share/php:/tmp:/usr/share/phpmyadmin:/etc/phpmyadmin:/var/lib/phpmyadmin) in /usr/share/roundcube/index.php on line 31

[Wed Aug 12 13:06:28 2015] [error] [client 76.xx.xx.24] PHP Warning: require_once(/usr/share/roundcube/program/include/iniset.php): failed to open stream: Operation not permitted in /usr/share/roundcube/index.php on line 31
[Wed Aug 12 13:06:28 2015] [error] [client 76.xx.xx.24] PHP Fatal error: require_once(): Failed opening required 'program/include/iniset.php' (include_path='.:/usr/share/php') in /usr/share/roundcube/index.php on line 31

Don't remember ever seeing this error before. Any idea where to start looking to fix this?

Thanks!!!

 

The contents of my /etc/apache2/conf.d/roundcube.conf file (which is a link to /etc/roundcube/apache.conf) is below:

Code:

# Those aliases do not work properly with several hosts on your apache server
# Uncomment them to use it or adapt them to your configuration
#    Alias /roundcube/program/js/tiny_mce/ /usr/share/tinymce/www/
#    Alias /roundcube /var/lib/roundcube
     Alias /webmail /var/lib/roundcube

# Access to tinymce files
<Directory "/usr/share/tinymce/www/">
      Options Indexes MultiViews FollowSymLinks
      AllowOverride None
      Order allow,deny
      allow from all
</Directory>

<Directory /var/lib/roundcube/>
  Options +FollowSymLinks
DirectoryIndex index.php

  <IfModule mod_php5.c>
    AddType application/x-httpd-php .php

    php_flag magic_quotes_gpc Off
    php_flag track_vars On
    php_flag register_globals Off
    php_value include_path .:/usr/share/php
  </IfModule>

  # This is needed to parse /var/lib/roundcube/.htaccess. See its
  # content before setting AllowOverride to None.
  AllowOverride All
  order allow,deny
  allow from all
</Directory>

# Protecting basic directories:
<Directory /var/lib/roundcube/config>
        Options -FollowSymLinks
        AllowOverride None
</Directory>

<Directory /var/lib/roundcube/temp>
        Options -FollowSymLinks
        AllowOverride None
    Order allow,deny
    Deny from all
</Directory>

<Directory /var/lib/roundcube/logs>
        Options -FollowSymLinks
        AllowOverride None
    Order allow,deny
    Deny from all
</Directory>

 

Decided to re-install from scratch since there was no production websites on it.

Thanks!