I have installed ispconfig 3 as per your debian dockument Every thing seems to work except the squirrel webmail. When you go to http://mail.example.co.za/webmail or http://196.111.111.111/webmail you get error 404 “The requested URL was not found on this server”. It does this on all domain names I have tried uninstalling and reinstalling squirrel but it did not help.
You can not access squirrelmail like this if the IP address you use is assigned to any of your websites.