I just created a site in ispconfig site section then i added these nginx Directives Code: server { listen 80; server_name www.smaalu.me smaalu.me; root /var/www/clients/client1/web1/web; if ($http_host != "www.smaalu.me") { rewrite ^ http://www.smaalu.me$request_uri permanent; } index index.php index.html; location = /favicon.ico { log_not_found off; access_log off; } location = /robots.txt { allow all; log_not_found off; access_log off; } # Deny all attempts to access hidden files such as .htaccess, .htpasswd, .DS_Store (Mac). location ~ /\. { deny all; access_log off; log_not_found off; } location / { try_files $uri $uri/ /index.php?$args; } # Add trailing slash to */wp-admin requests. rewrite /wp-admin$ $scheme://$host$uri/ permanent; location ~* \.(jpg|jpeg|png|gif|css|js|ico)$ { expires max; log_not_found off; } location ~ \.php$ { try_files $uri =404; include /etc/nginx/fastcgi_params; fastcgi_pass 127.0.0.1:9000; fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name; } } but same it is ERROR 500 - Internal Server Error! , Please help guys